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Nurtec ODT FAQ
Frequently Asked Questions

Actual
Nurtec ODT
Patients
Nurtec ODT is an orally disintegrating tablet proven to treat a migraine attack and prevent episodic migraine in adults.
Ask your doctor whether Nurtec ODT could be right for you.
Before starting Nurtec ODT, tell your doctor if you have liver or kidney problems. Tell your doctor if you are pregnant or plan to become pregnant, are breastfeeding or plan to breastfeed. It is not known if Nurtec ODT can harm your unborn baby. The amount of rimegepant present in breast milk is less than 1%.
People with a history of hypersensitivity to rimegepant or any of the components of Nurtec ODT should avoid taking Nurtec ODT. Allergic reactions such as trouble breathing and rash can occur, even days after taking Nurtec ODT. If you have symptoms of an allergic reaction such as trouble breathing or swelling of the face, mouth, tongue, or throat seek medical help right away.
If you need help talking to your doctor, try using our .
When people experience a migraine attack, they have elevated levels of a protein called calcitonin gene‑related peptide (CGRP) in the brain. These proteins attach to and activate receptors in the brain, which is believed to cause migraine attacks. Receptors help cells communicate and bring about responses, such as pain.
Nurtec ODT works by blocking CGRP receptors from being activated. This can help to treat and prevent migraine attacks. Nurtec ODT can also help stop the pain signals, swelling of blood vessels, and inflammation that occurs in the brain.
Nurtec ODT can be taken along with preventive medication for migraine, as long as the preventive medication is not another calcitonin gene-related peptide (CGRP) receptor antagonist. In the clinical trial for acute treatment of migraine, approximately 14% of patients were taking preventive medications for migraine at the start of the trial. Note that Nurtec ODT can also be taken to prevent migraine attacks, so ask your doctor about your treatment plan and make sure to discuss your current medications and treatment goals.
Nurtec ODT can start working fast. In the study for acute treatment of migraine attacks, some people taking Nurtec ODT were free from their migraine pain and most bothersome symptom in as soon as 2 hours. And some people were able to get back to normal activities in as soon as 60 minutes.
The study included 1351 people who took either Nurtec ODT or placebo to treat their migraine attacks. More people taking Nurtec ODT experienced freedom from pain, freedom from most bothersome symptom, normal functioning, and pain relief at 2 hours compared to placebo. More people taking Nurtec ODT were also able to maintain these benefits through 48 hours vs placebo. Additionally, more people taking Nurtec ODT experienced pain relief and freedom from functional disability as early as 60 minutes vs placebo.
In another study, people taking Nurtec ODT every other day for prevention experienced a greater reduction in monthly migraine days (MMDs) during weeks 9-12 than those taking placebo. The study included 695 people who took either Nurtec ODT or placebo to prevent their migraine attacks. People taking Nurtec ODT experienced 4.3 fewer MMDs during weeks 9-12 vs 3.5 fewer MMDs experienced by people taking placebo.
The most common side effects of Nurtec ODT were nausea (2.7%) and indigestion/stomach pain (2.4%).
Eligible patients with commercial insurance may pay as little as $0 per month.*
*Patients are not eligible to use this card if they are enrolled in a state or federally funded insurance program, including but not limited to Medicare, Medicaid, TRICARE, Veterans Affairs health care, a state prescription drug assistance program, or the Government Health Insurance Plan available in Puerto Rico. The offer will be accepted only at participating pharmacies. This offer is not health insurance. No membership fees apply. Pfizer reserves the right to rescind, revoke, or amend this offer without notice. For any questions, please call 1-800-761-1568. For full terms and conditions visit nurtec.com/savings#terms-and-conditions or write to Pfizer Inc. at PO Box 29387, Mission, KS 66201.
Nurtec ODT can be prescribed by healthcare professionals (HCPs) such as primary care physicians, neurologists, and headache specialists. Get help getting Nurtec ODT or finding an HCP.
Yes! Your healthcare provider may already be offering virtual consultations. Nurtec ODT has also partnered with Populus Media to help you access licensed medical providers who can help you manage your migraine treatment. These providers will evaluate you and make prescribing decisions based on their independent medical judgment.
If you are prescribed Nurtec ODT, you can fill your prescription at your local pharmacy or with at-home delivery. Learn more about your telemedicine options.

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6 things to talk to your doctor about
If you're still looking for the migraine treatment plan that's appropriate for you, it's time to talk to your doctor, whether in person or through .
Discuss your answers to these 6 questions with your doctor to help establish your treatment goals:
- How many days per month do you experience migraine pain?
- How long does the pain last and how intense is it?
- What symptoms do you experience before and during a migraine attack?
- What factors or events seem to trigger your migraine attacks?
- What over-the-counter or prescription medications have you taken for migraine in the past?
- Does anyone else in your family experience migraine attacks?
Giving your doctor a clear picture of your migraine experiences — including any current treatments — can help them determine whether Nurtec® ODT (rimegepant) 75 mg is a good option for you.