Frequently Asked Questions

Nurtec ODT is an orally disintegrating tablet proven to treat migraine attacks and help prevent episodic migraine in adults.

Ask your doctor whether Nurtec ODT could be right for you.

Before starting Nurtec ODT, tell your doctor if you have liver or kidney problems. Tell your doctor if you are pregnant or plan to become pregnant, are breastfeeding or plan to breastfeed. It is not known if Nurtec ODT can harm your unborn baby. The amount of rimegepant present in breast milk is less than 1%.

People with a history of hypersensitivity to rimegepant or any of the components of Nurtec ODT should avoid taking Nurtec ODT. Allergic reactions such as trouble breathing and rash can occur, even days after taking Nurtec ODT. If you have symptoms of an allergic reaction such as trouble breathing or swelling of the face, mouth, tongue, or throat seek medical help right away.

If you need help talking to your doctor, try using our Doctor Discussion Guide.

When people experience a migraine attack, they have elevated levels of a protein called calcitonin gene‑related peptide (CGRP) in the brain. These proteins attach to and activate receptors in the brain, which is believed to be a cause of migraine attacks. Receptors help cells communicate and bring about responses, such as pain.

Nurtec ODT works by blocking CGRP receptors from being activated. This can help to treat and prevent migraine attacks. Nurtec ODT can also help stop the pain signals, swelling of blood vessels, and inflammation that occurs in the brain.

Nurtec ODT can be taken along with preventive medication for migraine, as long as the preventive medication is not another calcitonin gene-related peptide (CGRP) receptor antagonist. In the clinical trial for acute treatment of migraine, approximately 14% of patients were taking preventive medications for migraine at the start of the trial. Note that Nurtec ODT can also be taken to help prevent migraine attacks, so ask your doctor about your treatment plan and make sure to discuss your current medications and treatment goals.

Nurtec ODT can start working fast. In the study for acute treatment of migraine with or without aura in adults, some people taking Nurtec ODT were free from their migraine pain and most bothersome symptom in as soon as 2 hours. And some people were able to get back to normal activities in as soon as 60 minutes.

The study included 1351 people who took either Nurtec ODT or placebo to treat their migraine attacks. More people taking Nurtec ODT experienced freedom from pain, freedom from most bothersome symptom, normal functioning, and pain relief at 2 hours compared to placebo. More people taking Nurtec ODT were also able to maintain these benefits through 48 hours vs placebo. Additionally, more people taking Nurtec ODT experienced pain relief and freedom from functional disability as early as 60 minutes vs placebo.

In another study, people taking Nurtec ODT every other day for prevention experienced a greater reduction in monthly migraine days (MMDs) during weeks 9-12 than those taking placebo. The study included 695 people who took either Nurtec ODT or placebo to prevent their migraine attacks. People taking Nurtec ODT experienced 4.3 fewer MMDs during weeks 9-12 vs 3.5 fewer MMDs experienced by people taking placebo.

The most common side effects of Nurtec ODT were nausea (2.7%) and indigestion/stomach pain (2.4%).

You may be eligible to pay as little as $0* out-of-pocket for a 30-day supply with your copay card. Learn more about how you could save and download your copay card using the button below.

see if you’re eligible

_{*Eligible commercially insured patients can, for one time only, access Nurtec ODT at no cost while benefits are being verified for one prescription fill, with a maximum of 16 tablets total. Insurance coverage must be approved by the payor for patients to continue receiving Nurtec ODT with no out-of-pocket cost. No membership fees. Only available for commercially insured patients. This is not health insurance. Maximum annual benefit of $7,000 applies. The full terms and conditions can be accessed at nurtec.com/terms-and-conditions.}

Nurtec ODT can be prescribed by healthcare professionals (HCPs) such as primary care physicians, neurologists, and headache specialists.